Mrs Rajaputana Lakshmi Manisha

Mrs Rajaputana Lakshmi Manisha |Clyto Access

Visveswarapura Institute of Pharmaceutical Sciences, India

Poster Presentation

Expertise: Barleria longiflora L.f., Potentilla anserina Linn, inflammation, carrageenan, edema

Biography:

Mrs Rajaputana Lakshmi Manisha doing PhD in pharmacology field from Visveswarapura Institute of Pharmaceutical Sciences, Bangalore, India which is affiliated by Rajiv Gandhi University of Health Science.She studied B.Pharm, at A.K.R.G college of pharmacy affliated to Andhra university, Andhra Pradesh, India. M.Pharm and PhD at RGUHS university, Bangalore, India.She is an associate member of the Association of Pharmaceutical Teacher of India, 2015 onwards.She have professional skill on the methods and drugs used for urolithiasis. She have publication in Novel Science International Journal of Medical Science, International Journal of Pharmaceutical Sciences and Research, The Global Journal of Pharmaceutical Research, Journal of Applied Pharmaceutical Science.

Presentation:

Title: Evaluation Of Anti-Inflammatory Activity Of Aqueous And Ethanolic Extracts Of Barleria Longiflora L.F. And Potentilla Anserina Linn

Abstract:

Inflammation is a body defence mechanism. The intent of this research was to perceive evidence if ayurvedic therapies be suitable and safe supportive to conventional drugs.

Aim: Evaluation of aqueous and ethanolic extract of leaf of Barleria longiflora L.f. and whole plant of Potentilla anserina Linn for anti-inflammatory activity using Carrageenan induced paw oedema in rats.

Materials and method: Animals were divided into 10 groups of 6 rats. Groups 1 and 2 served as Carrageenan induced control and standard (Diclofenac 5 mg/Kg, i.p.) respectively. Groups 3 and 4 were treated, orally with aqueous extract of Barleria longiflora L.f. with 100 and 400 mg/kg b.w, respectively. Groups 5 and 6 were administered, orally, ethanol extract of Barleria longiflora L.f. with 100 and 400 mg/kg b.w, respectively. Groups 7 and 8 were received, orally, aqueous extract of Potentilla anserina Linn of 100 and 400 mg/kg b.w, respectively. Groups 9 and 10 were administered, orally, ethanol extract of Potentilla anserina Linn of 100 and 400 mg/kg b.w, respectively. The paw volume was measured at 0, 1, 2, 3 and 4 hr after carrageenan injection. The actual edema volume was calculated. The data was expressed as mean ± S.E.M. The statistical analysis was done by means of ANOVA followed by Dunnett’s post hock test.

Results: The aqueous and ethanol extracts of both plants exhibited significant reduction of edema in the rats. Conclusion: Ethanol extract of Potentilla anserina Linn revealed superior anti-inflammatory activity.

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